Christina Applegate Posts New Photograph of Cheek Spot Amid MS Battle

Since her 2021 prognosis, Applegate has gotten used to the texture of an open-front robe. “I have been within the hospital upwards of 30 instances from throwing up and diarrhea and ache,” she relayed on her pocast in March 2025. “That’s unimaginable, OK? They’ve completed each check recognized to man on me, put a lot radiation into my physique from CT scans to all the pieces else.”

Within the plus column, she famous, she has related a few of her gastro points to her bigger sickness. “I’ve seen that—and I’m going to be actually sincere—if I’ve to poop, I puke,” she detailed. “And after I puke, I get all of the ache after which all of the issues occur.” 

Mere months after her hospital confession, Applegate was checking again in. Getting back from a household journey to Europe, “I am like, ‘I wanna be admitted. I am staying right here as a result of I would like solutions,'” she recounted that August of what she advised workers. “‘I would like each check which you could presumably consider or ones that you have not even considered, and I would like them completed.'”

Following a middle-of-the-night CT, she realized, “I had kidney infections.”